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Magazine articles
Open Access
Proper design and use of suction roll sealing strips in suction roll operation, TAPPI JOURNAL, November 1996, Vol. 79(11)

Proper design and use of suction roll sealing strips in suction roll operation, TAPPI JOURNAL, November 1996, Vol. 79(11)

Magazine articles
Open Access
Papermakers conference draws more than 900 attendees, TAPPI JOURNAL, July 1993, Vol. 76(7)

Papermakers conference draws more than 900 attendees, TAPPI JOURNAL, July 1993, Vol. 76(7)

Magazine articles
Open Access
Evolution and development of headbox systems for specialty nonwoven formers, TAPPI JOURNAL, February 1992, Vol. 75(2)

Evolution and development of headbox systems for specialty nonwoven formers, TAPPI JOURNAL, February 1992, Vol. 75(2)

Magazine articles
Open Access
Behavioral observation: gathering data for continuous safety improvement, TAPPI JOURNAL, February 1992, Vol. 75(2)

Behavioral observation: gathering data for continuous safety improvement, TAPPI JOURNAL, February 1992, Vol. 75(2)

Magazine articles
Open Access
Alkaline filler addition and retention, TAPPI JOURNAL, April 1992, Vol. 75(4)

Alkaline filler addition and retention, TAPPI JOURNAL, April 1992, Vol. 75(4)

Magazine articles
Open Access
Steam cycle passivation and corrosion protection, TAPPI JOURNAL, March 1990, Vol. 73(3)

Steam cycle passivation and corrosion protection, TAPPI JOURNAL, March 1990, Vol. 73(3)

Magazine articles
Open Access
Fifth international printing and graphic arts conference: a joint success, TAPPI JOURNAL, June 1991, Vol. 74(6)

Fifth international printing and graphic arts conference: a joint success, TAPPI JOURNAL, June 1991, Vol. 74(6)

Magazine articles
Open Access
Thermal bonding of nonwoven fabrics, TAPPI JOURNAL, July 1990, Vol. 73(7)

Thermal bonding of nonwoven fabrics, TAPPI JOURNAL, July 1990, Vol. 73(7)

Magazine articles
Open Access
Chemically structured kaolin: a new coating pigment, TAPPI JOURNAL, February 1990, Vol. 73(2)

Chemically structured kaolin: a new coating pigment, TAPPI JOURNAL, February 1990, Vol. 73(2)

Journal articles
Magazine articles
Open Access
Evaluation of rice straw for purification of lovastatin, TAPPI Journal November 2021

ABSTRACT: Cholesterol synthesis in the human body can be catalyzed by the coenzyme HMG-CoA reductase, and lovastatin, a key enzyme inhibitor, can reduce hypercholesterolemia. Lovastatin can be obtained as a secondary metabolite of Aspergillus terreus ATCC 20542. In this study, rice straw of lignocellulose was used in aeration and agitation bath fermentation in a 1-L flask, and a maximal crude extraction rate of 473 mg/L lovastatin was obtained. The crude extract was treated with silica gel (230•400 mesh) column chromatography. Ethyl acetate/ethanol (95%) was used as the mobile phase, and isolation was performed through elution with various ethyl acetate/ethanol ratios. The highest production rate of 153 mg/L was achieved with ethyl acetate/ethanol in a ratio of 8:2. The lovastatin gained from the crude extract was added to 12 fractions treated with 0.001 N alkali, and acetone was then added. After 24 h of recrystallization at 4°C, the extract underwent high-performance liquid chromatography. The purity had increased from 25% to 84.6%, and the recovery rate was 65.2%.